Reed’s Inc. Announces Proposed Public Offering of Common Stock

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Email Print Friendly Share NORWALK, Conn., Oct. 22, 2019 (GLOBE NEWSWIRE) — Reed’s Inc. (Nasdaq: REED), owner of the nation’s leading portfolio of handcrafted, all-natural beverages, today announced that it intends to offer shares of its common stock in an underwritten public offering. Reed’s also expects to grant to the underwriters of the offering a...
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患者来源肿瘤类器官药物开发平台正式推出

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Email Print Friendly Share 圣迭戈, Oct. 23, 2019 (GLOBE NEWSWIRE) — Crown Bioscience今天宣布推出一个新的肿瘤类器官药物开发平台,有望显著提高临床前药物研发的预测性和速度。 该平台的初始阶段提供了首个市场有售的三维体外PDX源性类器官(PDXO)模型,由CrownBio超过2500多个人源肿瘤异体移植(PDX)模型组成的独特特征模型库所生成。 PDXO在生物学上相当于具有高度预测性的体内PDX模型,两者都是癌症干细胞驱动疾病模型。PDXO的额外优势是体外系统固有的速度  和可扩展性,极其适合高通量、大规模筛选和同时对多个组合策略进行测试。 这些3D 体外 模型的开发采用源自Clevers实验室的同类最佳Hubrecht类器官技术(HUB)协议,保证了鲁棒性和可靠的可转化性。CrownBio获得了HUB的独家许可,可使用HUB的类器官技术提供临床前肿瘤药物开发和验证服务。 首先推出的PDXO模型涵盖10多种癌症类型。作为平台的第二阶段,HUB患者源性类器官(PDO)将于2020年第一季度通过CrownBio独  家提供。 “在CrownBio,我们率先开发了人源肿瘤移植模型,”CrownBio首席科学官Henry  Li博士表示。“我们的新样本库中包括经完善描述和注释的类器官和相匹配的体内PDX模型,为临床前药物的发现提供了一个前所未有的转化工作流。从 体外 到体内 的真正无缝转化首次成为可能。我们的模型注释还提供自动发现生物标志物的机会,从而提高我们预测病人反应的能力。” 患者相关的PDXO模型的其他优势包括保留其PDX肿瘤母本的基因、形态和病理生理属性。PDXO和PDX也显示相似的药理学特性。 “我们非常高兴地看到HUB类器官技术被成功应用于PDX源性类器官的开发,并由CrownBio提供给整个行业的更大范围使用”,HUB首席  执行Rob Vries博士表示。“这一开创性的系统为访问病人源性 体外 和 体内 模型的丰富样本库提供了渠道,在实际意义上将人数更多的癌症患者人口带入了实验室。” 与常规2D和3D系统相比,HUB器类官作为一种临床前肿瘤学工具,已被证实能通过传代和高质量的分析读数提供稳定一致的生长。类器   官生物样本库的创建还能保证不失去原有属性,以便进行后续研究或重复研究。 关于Crown Bioscience Inc Crown Bioscience是JSR Life  Sciences下属企业,是一家全球性的药物研究和开发服务公司,提供转化平台以推进肿瘤学、炎症和代谢性疾病的研究。凭借广泛的相关模型和预测工具组合,Crown      Bioscience使客户能够提供卓越的临床候选药物。如需获取更多信息,请访问: https://www.crownbio.com https://www.jsrlifesciences.com 关于HUB Hubrecht类器官技术(HUB)是由荷兰皇家科学院和乌得勒支大学医学中心创建的一家组织。HUB利用的是Hans   Clevers教授的开创性研究成果,他发现了从不同疾病患者的组织中培育干细胞衍生人类“迷你器官”(HUB类器官)的方法。这些类器官是HUB生物样本库的一   部分,其特征是基因组测序、表达谱以及对已知和实验药物的敏感性,以建立一个将遗传及转录信息与药物反应性相关联的数据库。HUB   提供其HUB类器官技术的专利使用许可,以及HUB生物样本库类器官的访问许可,用于临床前药物的筛选、发现、开发和验证。此外,HUB还在进行临床研究,以验证该技术作为伴随式诊断的用途。更多资讯请见 www.hub4organoids.eu。 传媒查询:Jody BarbeauCrown Bioscience...
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Galileo Acquisition Corp. Announces Closing of $138 Million Initial Public Offering

Email Print Friendly Share New York, NY, Oct. 22, 2019 (GLOBE NEWSWIRE) — Galileo Acquisition Corp. (NYSE: GLEO.U, the “Company”) announced today that it closed its initial public offering of 13,800,000 units, including the exercise in full of the underwriter’s over-allotment option to purchase up to an additional 1,800,000 units. The offering was priced at...
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Homes For Our Troops 3rd Annual Veterans Day Celebrity eBay Auction with Jake Tapper, George Clooney, and Wynonna Judd, to raise funds for severely injured post-9/11 Veterans

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Email Print Friendly Share TAUNTON, Mass., Oct. 21, 2019 (GLOBE NEWSWIRE) — Homes For Our Troops (HFOT), a nonprofit that builds and donates specially adapted custom homes for severely injured post-9/11 Veterans, announces its Veterans Day Celebrity eBay Auction campaign lineup. Jake Tapper, George Clooney, and Wynonna Judd are among the notable celebrities teaming up...
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Food Processing & Handling Equipments Market to Reach USD 207.6 Billion By 2026 | Reports And Data

Email Print Friendly Share New York, Oct. 21, 2019 (GLOBE NEWSWIRE) — Increasing Consumption due to increasing population, More demand for quality and healthy foods, increasing rate of urbanization, and due to increasing rate of industrialization are key factors contributing to high CAGR of Food Processing & Handling Equipment during the forecast period.  According to...
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Envisioning Peace: URI at The Commonwealth Club

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Email Print Friendly Share Left to right: The Rev. Victor H. Kazanjian Jr., Executive Director, URI; Rita Semel, First Global Chair, URI; and The Rt. Rev. William E. Swing, Founder and President of URI. San Francisco, Oct. 21, 2019 (GLOBE NEWSWIRE) — URI (United Religions Initiative) will be featured at The Commonwealth Club of California...
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Philadelphia 76ers and GIANT Tip Off New Partnership

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Email Print Friendly Share PHILADELPHIA, Oct. 21, 2019 (GLOBE NEWSWIRE) — Just in time for opening day of the NBA’S 2019-2020 season, the Philadelphia 76ers and GIANT Food Stores announced today a new multi-year partnership with a significant emphasis on community engagement. Through the partnership, GIANT will be named an official partner of the 76ers,...
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EarthRenew Announces $2 Million Private Placement

Email Print Friendly Share TORONTO, Oct. 21, 2019 (GLOBE NEWSWIRE) — EarthRenew Inc. (CSE:ERTH) (“EarthRenew” or the “Company”) is pleased to announce that it intends to complete a private placement financing of up to 40,000,000 common shares (each, a “Common Share”) at a price of $0.05 per Common Share for gross proceeds of up to...
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